Inject subcutaneously into the abdomen. Rotate injection sites regularly. Best administered on the same day each week.
Suggested Weekly Dosage Schedule/Injection Protocol*
Weeks 1–4
0.5mg once weekly
5 units on an insulin syringe
Weeks 5–8
1mg once weekly
10 units on an insulin syringe
Weeks 9–12
1.5mg once weekly
15 units on an insulin syringe
Weeks 13–16
2mg once weekly
20 units on an insulin syringe
Only increase dosage if well tolerated.
Break / Maintenance Phase
After completing a full cycle, some protocols include:
- a 2–4 week break, or
- a lower-dose maintenance phase before restarting.
- This approach may help support long-term appetite-regulation pathways and reduce adaptation over time.
Discover the benefits of Semaglutide 20mg for weight loss in South Africa.
Research Peptide:
Research suggests that Semaglutide may help regulate hunger signalling and gastric emptying pathways, contributing to increased feelings of fullness and reduced caloric intake. Due to its long active duration, Semaglutide is commonly utilised in once-weekly administration protocols with gradual dose progression.
Potential Research Areas
- Appetite regulation research
- Weight-management support pathways
- Metabolic health research
- Blood sugar regulation pathways
- Satiety and hunger signalling research
- Body composition research
- GLP-1 receptor pathway research
- Long-term metabolic efficiency studies
Common Notes
Some individuals may experience:
Protocols commonly recommend:
- gradual dose progression,
- adequate hydration,
- smaller meal sizes,
- avoiding heavy high-fat meals,
- and maintaining consistent weekly administration.
- These effects are commonly reported during adjustment phases and may improve over time.
Disclaimer
- For research purposes only
- Not intended to diagnose, treat, cure, or prevent any disease
- Not medical advice
- Use sterile procedures when handling peptides